Dr. Jai Prakash Muyal

Assistant Professor

University School Of BioTechnology
PhD (2006) Human Biology, Justus Leibig Univeristy, Giessen, GERMANY
Animal Biotechnology, Molecular Biology, Genomics, Cell Biology.



Jai Prakash Muyal (2021). Review article on Pulmonary Emphysema: An Inflammatory Lung

Disease. ACTA scientific microbiology. Volume 4 Issue 7.




1.  Importance of detection systems of real-time PCR for novel coronavirus-19 diagnosis. Mini Review - Journal of Biochemistry and Biotechnology (2021) Volume 4, Issue 1. Jai Prakash Muyal*, Basav Hazarika.

2. All Trans Retinoic Acid (ATRA) progresses alveolar epithelium regeneration by involving diverse signalling pathways in emphysematous rat. Biomed Pharmacotherapy (Elsevier). 2020 Nov; 131:110725. Uniyal S, Dhasmana A, Tyagi A, Muyal JP  Tyagi A, Muyal JP. Impact factor = 6.5 

3.  Effects of a Combined Therapy of ATRA+VEGF on Distal Organs of Emphysematous Mice Model. ACTA SCIENTIFIC MEDICAL SCIENCES Volume 4 Issue 9 September 2020. Shivangi Mishra1, Megha Neolia,  Sherya Patil, Amit Kumar Tyagi and Jai Prakash Muyal.. 

4. ATRA reduces inflammation and improves alveolar epithelium regeneration in emphysematous rat lung. Uniyal S, Dhasmana A, Tyagi A, Muyal JP. Biomed Pharmacother (Elsevier). 2018 Dec; 108:1435-1450. Journal of Biochemistry and Biotechnology  

5.   rHuKGF ameliorates protease/anti-protease imbalance in emphysematous mice. Kotnala S, Tyagi A, Muyal JP. Pulm Pharmacol Ther (Elsevier). 2017 Aug; 45:124-135.

6.  Swati Uniyal, Sudhir Kotnala, Ekta Teotia, Rahul Kumar, Amit Tyagi, Jai Prakash Muyal. ATRA modulates gluconeogenesis and triglyceride biosynthesis pathway of liver in elastase induced emphysematous rats. Journal of Experimental and Applied Animal Sciences. Volume 2, Number 2, pp. 109-125, 2017 Print ISSN 2314-5684 .

7.   Effects of intraperitoneal admistration of ATRA on the testis of elastase induced emphysematous rats.  Swati Uniyal, Nimisha Sharma, Sudhir Kotnala, Amit Tyagi, Jai Prakash Muyal.  Research & Reviews: Journal of Toxicology. Vol 6, No. 3 (2016).

8.  A Comparative Study on the Expression of Various Housekeeping Genes in the Organs of Different Mice Strains. Apurva Singh, Supriya Tyagi, Geetu Singh, Sudhir Kotnala, Swati Uniyal, Amit Tyagi, Jai Prakash Muyal. Research & Reviews: Journal of Biotechnology. VOL 5, NO 3 (2015).

9. Recombinant Human Keratinocyte Growth Factor Induces Akt Mediated Cell Survival Progression in Emphysematous MiceJP Muyal, D Kumar, S Kotnala, V Muyal, AK Tyagi. Archivos de Bronconeumología. 2015 Jul;51(7):328-37

10. Effect of recombinant human keratinocyte growth factor in inducing Ras–Raf–Erk pathway-mediated cell proliferation in emphysematous mice lungJP Muyal, S Kotnala, H Bhardwaj, A Tyagi. Inhalation toxicology 26 (13), 761-771. 2014.

11.   A Comparative Study on Production of Wine from Different Vegetables. K Tripathi, A Garg, P Singh, S Kotnala, JP Muyal. Research & Reviews: Journal of Food Science & Technology 3 (2), 1-5. 2014.

12. Abhinit Kumar Singh, Sudhir Kotnala, Ankit Maurya, Amit Kumar, and Jai Prakash Muyal. Effect of Moist Aeration towards Augmentation of Ascorbic Acid in Solanum tuberosum: A Molecular Approach. Research and Review: Journal of Food Science and Technology. Vol 2, No 3 (2013).

13.   Jai Prakash Muyal, Vandana Muyal, Sudhir Kotnala, Dhananjay Kumar, Harsh Bhardwaj. Therapeutic Potential of Growth Factors in Pulmonary Emphysematous Condition. Lung (Springer). 2013 Apr;191(2):147-63.

14.  Seifart CMuyal JPPlagens AYildirim AOKohse KGrau VSandu SReinke CTschernig TVogelmeier CFehrenbach H. ATRA results in irregular repair of septa and fails to inhibit proinflammatory macrophages. Eur Respir J. 2011 Jan 27. Impact factor 33.8 (2022)

15.  Jai Prakash Muyal, Vandana Muyal, Brajesh Pratap Kaistha, Carola Seifart, and Heinz Fehrenbach. Systematic Comparison of RNA Extraction Techniques from Frozen and Fresh Lung Tissues: Checkpoint towards Gene Expression Studies. BMC Diagnostic Pathology 2009; 4: 9.

16. Jai Prakash Muyal, Shiv Kumar Singh, & Heinz Fehrenbach. DNA-Microarray Technology: Impact of Methods Optimization Generated a Reliable Platform for the Gene Expression Profiling. Critical Reviews in Biotechnology, Volume 28, Issue December 2008 , pages 239 – 251.

17. Jochen Wilhelm, Jai Prakash Muyal, Johannes Best, Grazyna Kwapiszewska, Maria Magdalena Stein 1, Werner Seeger, Rainer Maria Bohle, and Ludger Fink. “Systematic comparison of the T&-IVT and SMART™ based RNA preamplification techniques for DNA-microarray experiments”- Clin Chem. 2006 Jun 52(6): 1161-7. PMID: 16627562.

18. Pullamsetti S, Kiss L, Ghofrani HA, Voswinckel R, Haredza P, Walter Klepetko, Aigner C, Fink L, Muyal JP, Weissmann N, Grimminger F, Seeger W, and Schermuly RT. “Increased levels and reduced catabolism of asymmetric and symmetric dimethylarginices in pulmonary hypertension” – FASEB J. 2005 Jul 19(9): 1175-7. PMID: 15827267.

19.  Ludger Fink,Hans Hölschermann, Grazyna Kwapiszewaska, Jai Prakash Muyal, Björn Lengemann, Rainer Maria Bohle, Santot Santoso. “Characterization of platelet-specific mRNA by real-time PCR after laser-assisted microdissection”- Thromb Haemost. 2003 Oct 90(4):749-56PMID: 14515198. 

Conference Proceedings

  1. Workshop on Artificial Intelligence and Machine learning Applications in the Emerging Areas of Computer Science and Information Technology organised by NITK, Suruthkal, Mangalore, between 09th -13th Dec, 2019.
  2. Workshop on Advanced Techniques in Genomics held between 22th-25th Jan, 2019 at Madras Diabetes Research Foundation, Chennai (MDRS) organised by MDRS and ICMR.
  3. Faculty Development Programme (FDP) on “Entrepreneurship, Motivation & Leadership” from 24th-30th December 2018, organized jointly by National Institute for Entrepreneurship and Small Business Development (NIESBUD) and ARSD College, University of Delhi.
  4. Faculty Development Programme (FDP) on “Effective Teaching and Learning Practices“ from 22th-26th  September 2018 organized by Shayama Prasad Mukherji College for Women, University of Delhi.
  5. Invited lecture on “Functional Genomics“ on 29th Aug 2018 at Medini, Botanical Society of Kirori Mal College, Delhi University, Delhi.
  6. Faculty Development Programme (FDP) on “Approaches for In Silico Drug Desigining“ Organized by the Department of Biotechnology, IILM Academy of Heigher learning, College of Engineering and Technology, Greater Noida, sponsored by Dr. A.P.J. Abdul Kalam Technical University, Luchnow, U.P. on 3rd July to 7th July 2018.
  7. National conference on Recent Trends in Cell and Molecular Biology Research Organized by Department of Life Sciences, Shiv Nadar University, Greater Noida on 27th -28th October 2017.
  8. National Workshop on Biostatistics held on 9-10 March 2017, organised by Department of Mathematics and Botany at Zakir Husain Delhi College, University of Delhi.
  9. National conference on “Development and Advancement in Conservation, Propagation and Sustainable Utilization of Medicinal Plants” held on 20th-21st January 2017 at School of Biotechnology, Gautam Buddha University.
  10. National conference on intellectual property rights (IPR), held on 16-17 December 2016, Organized by PHD chamber of Commerce and Industry, New Delhi in collaboration with DIPP-IPR, University of Delhi.
  11. National WORKSHOP on “Changing Paradigm of Pedagogy”(the method and practice of teaching and learning) held on 29th December 2016, organized by Delhi College of Arts & Commerce, University of Delhi.
  12. Faculty Development Programme (FDP) on Research Data Analysis Using “EXCEL and SPSS” organized by Hans Raj Collage, University of Delhi on November 16, 2016.
  13. Jai Prakash Muyal, Alexandra Plagens, Claudia wild, Heinz Fehrenbach, Claus Vogelmeier, and Carola Seifart. Effects of Keratinocyte Growth Factor (KGF) on Matrix Metalloproteinases (MMPs) & Tissue Inhibitors of Metalloproteinases (TIMPs) mRNA levels in rats with elastase induced emphysema. Talk presented in ERS Oct 2008, Berlin, Germany International Conference.
  14. Jai Prakash Muyal, Alexandra Plagens, Manuel Herrmann, Claus Vogelmeier, Heinz Fehrenbach and Carola Seifart. Long-Term Influence of Recombinant Human Vascular Endothelium Growth Factor- (rhVEGF-) 165 on Surfactant Protein- (SP-) A and D mRNA Levels in Emphysematous Rats Lungs. Thematic Poster presented in ERS Oct 2008, Berlin, Germany International Conference.
  15. Jai Prakash Muyal, Alexandra Plagens, Ali Önder Yildirim, Sabine Mühlhofer, Heinz Fehrenbach, Claus Vogelmeier, and Carola Seifart. Expression of matrix metalloproteinase (MMPs) and TIMPs in rat alveolar macrophages (whole lung tissue) is modulated by ATRA in emphysematous lung. Thematic Poster presented in ERS 2007, 15-19 September, Stockholm, Sweden International Conference.
  16. Jai Prakash Muyal, Alexandra Plagens, Ali Önder Yildirim, Sabine Mühlhofer, Heinz Fehrenbach, Claus Vogelmeier, and Carola Seifart. Surfactant proteins expression in elastase induced emphysema – change after ATRA treatment? Talk presented in ERS-2007, 15-19 September, Stockholm, Sweden International Conference.
  17. Jai Prakash Muyal, Alexandra Plagens, Ali Önder Yildirim, Sabine Mühlhofer, Heinz Fehrenbach, Claus Vogelmeier, and Carola Seifart. Expression of MMPs and TIMPs in rat alveolar macrophages (AM) is modulated by ATRA in emphysematous lung. ATS 2007 San Francisco 103th International Conference.
  18. S. Kohlhoff, JP. Muyal, G. Kwapiszewska, MM. Stein, J. Hanze, N. Weissmann, F. Rose, W. Seeger, RM. Bohle, L. Fink. “Hypoxia induced expression profile differences from laser microdissected lung vessels and alveolar spetum cells. Array User Conference (RZPD), DKFZ-Heidelberg, 14-16.05.2003, Germany.