Dr. Vikrant Nain

Assistant Professor

University School Of BioTechnology
Phd Biotechnology
Recombinant DNA technology, Genome Editing, Genomics, Molecular Diagnostics



Book Chapters

  1. A Bhardwaj, A Solanki, V Nain  (2021) A Bioinformatics Perspective on Artificial Intelligence in Healthcare and Diagnosis: Applications, Implications, and Limitations. Advanced AI Techniques and Applications in Bioinformatics, 227-242.
  2. V Nain , S Sahi, PA Kumar (2011).In silico identification of regulatory elements in promoters. Computational biology and applied bioinformatics. In Tech, 47-66


Sl. No.

Inventor/s Name

Title of the Patent

Patent Application No.


Nain Vikrant, Tomar Pradeep, Suman

Synthetic gene coding for FokI nuclease domain in programmable nucleases for genome editing



Nain Vikrant, Tomar Pradeep, Suman

Synthetic gene coding for TET1 catalytic domain in programmable enzymes for epigenome editing



Nain Vikrant, Tomar Pradeep, Suman

Synthetic gene coding for p65 subunit of NF-Kappa B transcription activation domain in programmable transcription factors



Nain Vikrant, Tomar Pradeep, Suman

Synthetic gene coding for VP64 transcription activation domain in programmable transcription factors



Nain Vikrant, Tomar Pradeep, Suman

Synthetic gene coding for KRAB transcription repression domain in programmable transcription repressors



  1. VK Singh, ML Phanindra, V Nain , S Gothandapani, G Dhandapani, K.R.S. Sambasiva Rao, A Kumar, PA Kumar, (2022) Targeting delta-endotoxin (Cry1Ac) of Bacillus thuringiensis to subcellular compartments increases the protein expression, stability, and biological activity, International Journal of Biological Macromolecules,205: 185-192
  2. VK Singh, V Nain , MLV Phanindra, S Gothandapani, SS Chhapekar,  (2022) Rifampicin Increases Expression of Plant Codon-Optimized Bacillus thuringiensis δ-Endotoxin Genes in Escherichia coli. The Protein Journal, 1-10
  3. M Chaudhary, V Nain , D Sehgal (2021) Molecular docking and dynamic simulation analysis of Hepatitis E virus protease in complexing with the E64 inhibitor. Journal of Biomolecular Structure and Dynamics, 1-9
  4. A Bhardwaj, V Nain  (2021) TALENs—an indispensable tool in the era of CRISPR: a mini review. Journal of Genetic Engineering and Biotechnology 19 (1), 1-10
  5. S Pal, S Tiwari, R Puria, V Nain , R Prasad Pathak (2021) ICMPC Impact of ureolytic and nonureolytic bacteria on self healing of artificial cracks in biofortified concrete. Advances in Materials and Processing Technologies, 1-20
  6. Suman, M Chaudhary, V Nain  (2021) In silico identification and evaluation of Bacillus subtilis cold shock protein B (cspB)-like plant RNA chaperonesJournal of Biomolecular Structure and Dynamics 39 (3), 841-850
  7. A Prajapati, V Nain  (2021) Screening of CRISPR/Cas9 gRNA for mimicking Powdery Mildew resistant MLO ol-2 mutant. Bioinformation 17 (6), 637-645
  8. C Aggarwal, S Paul, V Nain , V Tripathi, B Paul, MA Khan (2021).  Comparative response of Spodoptera litura challenged per os with Serratia marcescens strains differing in virulence. Journal of Invertebrate Pathology 183, 107562
  9. A Chandra, M Chaudhary, I Qamar, N Singh, V Nain  (2021).In silico identification and validation of natural antiviral compounds as potential inhibitors of SARS-CoV-2 methyltransferase. Journal of Biomolecular Structure and Dynamics, 1-11
  10. A Awasthi, V Nain , CV Srikanth, R Puria (2020). A regulatory circuit between lncRNA and TOR directs amino acid uptake in yeast.  Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1867 (6), 118680
  11. Suman, V Nain  (2020). In Silico Designing of Xa13 Locus Specific TALENs for Introducing Bacterial Blight Resistance in Rice.  Indian Journal of Pure & Applied Biosciences 8 (2), 389-402
  12. Y Ahmad, V Nain   (2020) A convenient and robust protocol for preparation of ODAP-free Lathyrus sativus protein. Analytical Biochemistry 591, 113544
  13. A Awasthi, V Nain , R Puria (2019). MYOD and HAND transcription factors have conserved recognition sites in mTOR promoter: insights from in silico analysis Interdisciplinary Sciences: Computational Life Sciences 11 (2), 329-335
  14. P Rawal, H Siddiqui, M Hassan, MC Choudhary, DM Tripathi, V Nain ,  (2019) Endothelial cell-derived TGF-β promotes epithelial-mesenchymal transition via CD133 in HBx-infected hepatoma cell. Frontiers in oncology 9, 308
  15. P Kumar, D Kundu, AK Mondal, V Nain , R Puria (2019) Inhibition of TOR signalling in lea1 mutant induces apoptosis in Saccharomyces cerevisiae. Annals of Microbiology 69 (4), 341-352
  16. Suman, R Puria, V Nain  (2019). KasI vs. SspDI: Comparative analysis of enzyme activity for restriction digestion. NISCAIR-CSIR, India
  17. S Tiwari, S Pal, R Puria, V Nain , RP Pathak (2019) Mechanical and Microstructure Study of the Self Healing Bacterial Concrete. Materials Science Forum 969, 472-477
  18. S Tiwari, S Pal, R Puria, V Nain , RP Pathak (2018).Microbial Crack Mechanical Strength Bacterial C. International Journal of Civil Engineering 9 (13)
  19. P Kumar, A Awasthi, V Nain , B Issac, R Puria (2018).Novel insights into TOR signalling in Saccharomyces cerevisiae through Torin2.Gene 669, 15-27.
  20. A Awasthi, V Nain , H Singh, P Kumar, R Puria (2018). Targeting Cancer cell metabolism via Target of Rapamycin. Current Trends in Biotechnology and Pharmacy 12 (2), 196-205
  21. A Sharma, V Nain , R Tiwari, S Singh, L Nain (2018).Optimization of fermentation condition for co-production of ethanol and 2,3-butanediol (2,3-BD) from hemicellolosic hydrolysates by Klebsiella oxytoca XF7.Chemical Engineering Communications 205 (3), 402-410
  22. S Tiwari, S Pal, R Puria, V Nain  (2017). A Review on Biofortified Self-Healing Concrete Construction Materials and Systems, 91
  23. A Sharma, V Nain , R Tiwari, S Singh, A Adak, PKS Nain, L Nain (2017). Simultaneous saccharification and fermentation of alkali-pretreated corncob under optimized conditions using cold-tolerant indigenous holocellulase. Korean Journal of Chemical Engineering 34 (3), 773-780
  24. VK Singh, V Nain , P Sharma, KRSS Rao, A Birah, GP Gupta, PA Kumar (2015). Enhanced Toxicity of Purified Bacillus thuringiensis Cry1Ac δ-endotoxin. Current Trends in Biotechnology and Pharmacy 9 (3), 243-250.
  25. GK Goswami, M Krishnamohan, V Nain , C Aggarwal, B Ramesh (2014). Cloning and heterologous expression of cellulose free thermostable xylanase from Bacillus brevis. SpringerPlus 3 (1), 1-6.
  26. V Nain , R Buddham, R Puria, S Sahi (2014). Role of TCA cycle truncation in cancer cell energetics. Current Trends in Biotechnology and Pharmacy 8 (4), 428-438
  27. S Sahi, U Raj, M Chaudhary, V Nain  (2014). Modelling of human leucyl aminopeptidases for in silico off target binding analysis of potential Plasmodium falciparum leucine aminopeptidase (PfA-M17) specific inhibitors. Recent patents on endocrine, metabolic & immune drug discovery 8 (3), 191-201.
  28. S Sahi, S Rai, M Chaudhary, V Nain  (2014). Modeling of human M1 aminopeptidases for in silico screening of potential Plasmodium falciparum alanine aminopeptidase (PfA-M1)  specific inhibitors. Bioinformation 10 (8), 518
  29. VK Singh, S Gothandapani, MLV Phanindra, V Nain , R Sreevathsa, (2014). Vacuolar Targeting of Cry1Ac and its Effects on Expression and Stability in Tobacco. Current Trends in Biotechnology and Pharmacy 8 (3), 276-287
  30. R Puria, S Sahi, V Nain  (2012). HER2+ breast cancer therapy: by CPP-ZFN mediated targeting of mTOR? Technology in cancer research & treatment 11 (2), 175-180
  31. D Shrivastava, M Dalal, V Nain , PC Sharma, PA Kumar (2011). Targeted Integration of Bacillus thuringiensis delta-Endotoxin cry 1 Fa 1 in Brinjal(Solanum melongena L.) Current Trends in Biotechnology and Pharmacy 5 (2), 1149-1156
  32. P Sharma, V Nain , S Lakhanpaul, PA Kumar (2011). Binding of Bacillus thuringiensis Cry1A toxins with brush border membrane vesicles of maize stem borer (Chilo partellus Swinhoe). Journal of invertebrate pathology 106 (2), 333-335
  33. D Shrivastava, V Nain , S Sahi, A Verma, P Sharma, PC Sharma, ...(2011). Insights from molecular modeling and dynamics simulation of pathogen resistance (R) protein from brinjal Bioinformation 5 (8), 326

Conference Proceedings

Conference Proceedings in Research Journals

  1. Rawal, DM Tripathi, SK Sarin, V Nain , S Kaur (2020). Targeting HBx by CRISPR/Cas9 System Effectively Reduces the EMT and Stemness Characteristics of HCC Cells In Vitro. Journal of Hepatology 72, 61A-61A
  2. P Rawal, DM Tripathi, V Nain , S Kaur (2020). Crispr/cas9-tailored hepatitis Bx protein knockdown inhibits cellular hyperplasia, invasion and tumorigenicity of HBV-infected hepatoma cells. Journal of Hepatology 73, S843-S844
  3. PR Rawal, MH Bhat, S Rohilla, H Siddiqui, M Choudhary, V Nain  (2018).Endothelial Cells Enhance Invasive Properties of HBx-Transfected Hepatoma Cells By Inducing Epithelial-Mesenchymal Transition. Journal of Hepatology 68, 1271A-1271A
  4. I Kaur, S Rohilla, A Gupta, D Tripathi, J Maras, V Nain , S Sarin, S Kaur (2019). A study of liver LGR5+ Stem cells in acute and chronic liver injury. Journal of Gastroenterology and Hepatology 34, 71-71
  5. R Agarwal, S Kumari, V Nain , S Sahi (2011). Virtual screening studies for identification of novel antimalarials Journal of Natural Science, Biology and Medicine 2 (3)